South Sydney have suffered four losses on the bounce after a previously positive start to life under Wayne Bennett's watch.
The Rabbitohs have a mounting injury toll to deal with but will welcome Latrell Mitchell back after the fullback served his one-match ban in Magic Round.
Can the Bunnies get back to winning ways when they take on Brisbane?
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South Sydney Rabbitohs NRL game this week
The Rabbitohs will take on the Broncos at Accor Stadium on Friday, May 9 at 8:00 pm (AEST).
Rabbitohs predicted team list vs. Broncos for Round 10
1. Latrell Mitchell
2. Bayleigh Bentley-Hape
3. Euan Aitken
4. Campbell Graham
5. Isaiah Tass
6. Josh Schuster
7. Jamie Humphreys
8. Sean Keppie
9. Jayden Sullivan
10. Tevita Tatola
11. Keaon Koloamatangi
12. Tallis Duncan
13. Jai Arrow
14. Lewis Dodd
15. Liam Le Blanc
16. Lachlan Hubner
17. Davvy Moale
Rabbitohs latest team news for Round 10
The Bunnies have been decimated by injuries and suspensions in recent weeks, although they are set to be boosted by the returns of Latrell Mitchell and Jamie Humphreys.
Mitchell will take over at fullback after serving his one-game ban for a high shot, while Humphreys will return at halfback.
He could be partnered in the halves by Josh Schuster, who crossed for a try and provided two assists in the No.6 jersey for Souths during their loss to Newcastle in the NSW Cup.
However, despite those positive inclusions, Jye Gray and Peter Mamouzelos are set to be added to the casualty ward after both youngsters suffered injuries during their side's heavy loss to the Knights.
Mamouzelos could be replaced by Jayden Sullivan at hooker with Siliva Havili in doubt after missing Magic Round.
Lewis Dodd is likely to drop out of the starting side but could keep his spot in the 17 to act as the utility with Fletcher Myers going to the reserves.
Sean Keppie struggled up front and could lose his spot in the starting side with Davvy Moale applying pressure.
Alex Johnston, Tyrone Munro, Mikaele Ravalawa, Jack Wighton and Cody Walker remain on the sidelines.